IPF Idiopathic Pulmonary Fibrosis

damn! – I was just getting the hang of being happy!

Is this a ray of hope?

6 Comments

Here in the UK in the year I was told I have IPF (Idiopathic Pulmonary Fibrosis) 5,000 others received the same news. Somewhere between 3 and 4,000 have already died. They didn’t last long enough for a cure which will probably come from genomic developments – so said my consultant.

*If you know of anyone in a relevant field please let me know.*

This may or may not be genomic but it is the first ray of hope (I think) that I’ve seen for a long time;

An intriguing article that cuts through the fluff and talks about the realities of finding a cure for IPF. Both Esbriet and Nindetab are mentioned.
The IPF-associated protein that Elias’s team found—CHI3L1—“has been retained over species and time…We knew Mother Nature doesn’t do this unless it is very important.” When his team looked into it, they found CHI3L1 helps “stop cell death, while stimulating fibrosis and repair. It is a primordial, and fundamental, defense mechanism.”
Hunninghake wrote in the NEJM a revolution may be afoot. The new IPF drug trial results alone are “a major breakthrough….We may soon have choices in the medical management of pulmonary fibrosis.” It is even “reasonable to shift our understanding of the pathogenesis of this disease. It is now clear that (IPF) is a disease perpetuated by aberrant wound healing, rather than primarily by chronic inflammation.”
In part it says: “Via further experiments, Elias’ team found IPF is, in part, caused by fibrotic healing run amuck, trying to keep up with IPF’s ceaseless lung injury. Why is it ceaseless? “The injury process is still enigmatic.” But it is real. Doctors find, in autopsy, IPF patients’ lungs possess old scarring over old injuries—and fresh scarring over new ones.
Elias, and the team of Yale Translational Lung Research Director Erica Herzog, are further investigating IPF mechanisms. They are also screening for drugs. They have identified an antibody they will turn into a drug via the above (CADET) grant for lung drug design.”
“We are very excited about this whole area. We plan to stay in it for a while.”
Idiopathic Pulmonary Fibrosis: Hope, At Last
There have been stunning “firsts” in research on idiopathic pulmonary fibrosis (IPF), a mysterious disease that stiffens and stills the lungs, killing half its victims in three years. In May, results of Phase 3 clinical trials on the first two effective drugs for IPF were published in the New Englan…
biosciencetechnology.com

see http://www.biosciencetechnology.com/search/site/IPF

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Author: Roger - Dr Roger Prentice

Now I write, teach & coach mainly about interfaith as inter-spirituality - and how we can grow closer to our True Self. . As anyone who knows anything about IPF will realize my energy is curtailed - so I am concentrating primarily on 'inter-spirituality'. . In the past I would have said that: . 1) I run courses and give talks at conferences and in universities and colleges in the UK, China, USA, Canada, Scandinavia etc. . 2) I provide materials, outlines and lessons for Schools. . 3) My range of interests include personal development, learning and teaching, photography and film, the arts generally, spirituality and educational practice and theory. . 4) At the same time I continue developing the human-centred studies SunWALK PDS (People Development System) - a whole-person, high-achievement model for individuals, and for use in, NGOs, schools and other organizations. . 5) The key question that continues to animate me and my work remains, "What is it to be fully and positively human?" . Contact me via onesummit AT gmail DOT com (replace At with@ etc.). . All good wishes Roger (Dr Roger Prentice) . For those interested; My first degree is in English and Education. My masters is in Adult and Community Education. My doctorate presented a new holistic meta-model of education called SunWALK.

6 thoughts on “Is this a ray of hope?

  1. Have you considered asking to be tested for Herpes saimiri? A publication last year (2014), and several in the decade before that, implicate herpes viral infection as being extrememly strongly correlated with IPF. There’s a suggestion that an anti-viral might halt the disease, though replacing the already built up scar tissue (fibrotic tissue) with healthy normal lung tissue is not anywhere on the horizon right now. If I had IPF, I’d be doing my best to get my doctor to prescribe an anti-viral.

  2. What do you know about stem cell therapy for IPF?

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